NEW

The weight loss program that works

Achieving lasting results is now easier with personalized tools and a flexible weight loss program built by Mayo Clinic experts.

Get a free Personalized Plan

NEW

The weight loss program that works

Achieving lasting results is now easier with personalized tools and a flexible weight loss program built by Mayo Clinic experts.

Get a free Personalized Plan

Our successful weight loss program

Our successful weight loss program

The Mayo Clinic Diet is a trusted weight loss program developed by Mayo Clinic’s team of health and nutrition experts.

This much-loved program is designed to help you build sustainable habits, replace unhealthy behaviors, and achieve meaningful weight loss.

Updated with new tools, delicious meal plans and personalization features, the Mayo Clinic weight loss program supports a healthier lifestyle you can maintain for life.

Get a free Personalized Plan
Our successful weight loss program

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Why choose the Mayo Clinic Diet

Why choose the Mayo Clinic Diet

The Mayo Clinic Diet is a doctor-developed weight loss program backed by research and clinical experience.

The program is flexible, personalized to your needs, and supported by digital tools like a food journal and weight tracker to help you stay on track.

Key features of the Mayo Clinic weight loss program include:

  • Personalized weight loss plans
  • Emphasis on enjoyable, nutritious foods
  • Encourages physical activity
  • Comprehensive digital weight tracker
  • Lifestyle coaching support
About the program
Why choose the Mayo Clinic Diet

Real food,
flexible meal plans

Real food,
flexible meal plans

You'll love our 8 delicious meal plans designed to make weight loss simple, nutritious and tasty.

Explore meal plans

Real food,
flexible meal plans

Simple

Spend less time in the kitchen, more time living with our most popular meal plan full of delicious quick recipes.

Simple meal plan

Real food,
flexible meal plans

Mediterranean

A plant-based meal plan featuring fish, nuts, legumes and unlimited vegetables and fruits. 

Mediterranean meal plan

Real food,
flexible meal plans

Healthy Keto

A low-carb meal plan high in healthy fats which keeps daily net carbs to around 50 grams.

Healthy Keto meal plan

Real food,
flexible meal plans

The "Original"

A DASH-aligned meal plan following the eating plan from The Mayo Clinic Diet, Third Edition book. 

Original meal plan

Real food,
flexible meal plans

Vegetarian

A meat-free, plant-packed meal plan suitable for lacto-ovo vegetarians.

Vegetarian meal plan

Real food,
flexible meal plans

Higher Protein

This tasty meal plan distributes protein evenly across each meal of the day to help curb cravings.

Higher Protein meal plan

Why doctors recommend the Mayo Clinic Diet

5.3%
Average weight loss from the Mayo Clinic Diet digital program*
80%
More weight loss from the digital program vs an in-person experience*
13%
Average weight loss of responders to the Mayo Clinic Diet†
*Acosta, et al. (2024): Efficacy of in-person versus digital enhanced lifestyle interventions in adults with overweight and obesity, Obesity Pillars, Volume 12, 2024, 100133. https://doi.org/10.1016/j.obpill.2024.100133 † Mayo Clinic Diet - Weight Loss and Platform Usage: An analysis of Responders, Digital Wellness Report, August 2024

Why members love the Mayo Clinic Diet

Dr. Donald Hensrud, author of The Mayo Clinic Diet

This diet is not a fad. You’ve had enough of those and know the result. This is a program that helps you make simple, healthy, pleasurable changes that will result in a weight you can maintain for the rest of your life.

Donald D. Hensrud, MD, MS, MPH

The Mayo Clinic Diet is featured in 10 of 11 “Best Diets” categories by U.S. News & World Report

Frequently asked questions

What’s included in the Mayo Clinic Diet?

All these features are available the moment you join:

  • Evidence-based program, trusted worldwide – developed by physicians and dietitians at Mayo Clinic.
  • 12-week interactive course that teaches the proven “Lose It! --> Live It!” framework for safe, sustainable weight loss. Some courses are 24 weeks for extra support.
  • “Lose It!” quick-start (first 2 weeks) – jump-start results with a science-backed target of 6–10 lbs weight loss.
  • Digital tools (web + iOS/Android):
    • Food & exercise tracker (over 1 million foods with barcode scanner)
    • Weight, measurement and habit trackers
    • Automatic device sync (Apple Health, Google Fit)
  • Habit Optimizer and 100-point “Diet Score” – daily feedback on five core behaviors so you know exactly where to focus.
  • Unlimited group coaching plus optional 1-on-1 dietitian sessions for questions and accountability.
  • 1,400+ recipes that are quick, family-friendly, and budget-minded – calorie counting not required.
  • At-home workouts – equipment-free sessions that fit any schedule.
  • Mindset assessments and private members-only Facebook community for extra motivation and peer support.

How long is the program?

  • Core curriculum: 12 weeks (Lose It! = 2 weeks --> Live It! = 10 weeks).
  • Specialized programs: 24 weeks for extra support e.g. our Heart Health and Weight-Loss Medications (GLP-1) programs.
  • Lifetime support: Your membership continues as long as you choose. Most members stay for at least 6-12 months so they have support as their goals evolve.

How does the program work?

The Mayo Clinic Diet program works by combining evidence-based nutrition guidance, personalized planning, and digital tools to support long-term, healthy weight loss. Here's how the program works:

  • Mayo Clinic Diet Score: A unique 100-point scoring system that helps you make smarter food choices. The higher your Diet Score, the greater your potential for sustainable weight loss. Members with high scores often experience life-changing results.
  • 8 delicious meal plans: Choose from 8 customizable, nutritionally balanced meal plans, including options like Healthy Keto, Mediterranean, Heart Smart Superfoods, and Protein Balance for those using GLP-1 medications. Each plan is designed using a proven food group system, and members can also follow our Freestyle Guide for flexibility.
  • Personalized weight loss programs: The program can be tailored to support specific health needs such as diabetes or heart disease. There's also a dedicated support program for people taking weight-loss medications like GLP-1s, helping manage side effects and preserve muscle mass.
  • Unlimited group coaching: Get expert support through unlimited live coaching sessions with registered dietitians and Mayo Clinic experts. Topics include nutrition, exercise, medication guidance, and using the program effectively. One-on-one coaching is also available for eligible members.
  • Digital tools and community support: The program includes a food tracker, habit tracker, grocery lists, at-home exercise plans, integration with fitness devices, and access to a supportive member community. Additional resources like ebooks and Freestyle Guides help make the program easy to follow.

In short, the Mayo Clinic Diet is more than a diet—it’s a comprehensive, medically backed weight loss program that gives you the tools, flexibility, and expert support to build healthier habits for life.

What makes the Mayo Clinic Diet different from other online weight loss programs?

Where many diets stop

Where Mayo Clinic Diet excels

Weight loss only

Whole-health focus – nutrition, habit change, movement, sleep and stress.

Influencer-built

Clinician-built – rooted in years of Mayo Clinic medical expertise.

One-size-fits-all menus

8 flexible meal plans with personalization via swap tools and the ability to "freestyle" to make the menus your own.

Calorie math and extremes

No calorie counting; unlimited fruit and vegetables with balanced portions.

Little follow-up

Unlimited group coaching and community so you’re not in this alone.

Do I have to count calories?

No. The program teaches a food group “building-block” method – fill your plate with unlimited fruits and vegetables, then add lean protein, smart carbohydrates, and healthy fats. Portion visuals and the Diet Score keep you on track without spreadsheets.

What if I’m vegan, vegetarian or keto?

The platform lets you choose (and freely switch between) eight delicious meal plans.

Highlights

Meal plan

Ideal for

Quick snapshot

Simple

Busy schedules

Ready-prepped ingredients, 15-minute meals, gluten-free option

Healthy Keto

Low-carb lovers

~50 g net carbs, heart-healthy fats such as olive oil and avocado

Vegetarian

Plant-forward eaters

Lacto-ovo; protein via beans, soy, eggs, and dairy

Mediterranean

Heart health

Emphasizes fish, nuts, legumes, extra-virgin olive oil

Higher Protein

Appetite control & muscle support

Even protein distribution at each meal

Heart Smart Superfoods

Cholesterol / blood-pressure concerns

DASH-aligned, anti-inflammatory, cardio-protective foods

The “Original”

Classic Mayo approach

Based on the best-selling Mayo Clinic Diet book

GLP-1 Support

Members using weight-loss medications

Higher protein, lower-volume portions

Every meal plan includes a swap tool and grocery list, so accommodating dietary needs is as simple as one click.

Next step: Explore all meal plans or take a free Diet Score assessment .

Does your weight loss program work for both men and women?

Yes. The program is built to deliver safe, sustainable weight loss for adults of any gender.

  • Personalized targets – After joining, you enter your sex, age, height, weight and goals; the platform then assigns targets that reflect women and men’s weight loss needs.
  • Flexible meal plans scale easily – Every recipe and daily menu shows standard servings plus quick adjustments so you can increase or reduce portions without changing the core foods.
  • Success stories from both sexes – Program results highlight women such as Gail (lost 50 lbs) and Mouna (lost 52 lbs) alongside men like Richard (lost 56 lbs), demonstrating comparable, sustainable outcomes.
  • Universal habit-change framework – The “Lose It! --> Live It!” approach focuses on behaviors (fruit/vegetable intake, daily activity, mindful eating, goal setting) that improve metabolic health for everyone.
  • Coaching adapts to life stages – Registered dietitians can tailor guidance for menopause, men’s health, or other sex-specific concerns in optional 1-on-1 sessions.

Bottom line: Whether you’re male or female, the Mayo Clinic Diet’s evidence-based personalization, adaptable meal plans, and group coaching provide an effective path to lasting weight loss and better overall health.