The Mayo Clinic Diet is a trusted weight loss program developed by Mayo Clinic’s team of health and nutrition experts.
This much-loved program is designed to help you build sustainable habits, replace unhealthy behaviors, and achieve meaningful weight loss.
Updated with new tools, delicious meal plans and personalization features, the Mayo Clinic weight loss program supports a healthier lifestyle you can maintain for life.
Get a free Personalized PlanThe Mayo Clinic Diet is a doctor-developed weight loss program backed by research and clinical experience.
The program is flexible, personalized to your needs, and supported by digital tools like a food journal and weight tracker to help you stay on track.
Key features of the Mayo Clinic weight loss program include:
You'll love our 8 delicious meal plans designed to make weight loss simple, nutritious and tasty.
Explore meal plansSpend less time in the kitchen, more time living with our most popular meal plan full of delicious quick recipes.
Simple meal planA plant-based meal plan featuring fish, nuts, legumes and unlimited vegetables and fruits.
Mediterranean meal planA low-carb meal plan high in healthy fats which keeps daily net carbs to around 50 grams.
Healthy Keto meal planA DASH-aligned meal plan following the eating plan from The Mayo Clinic Diet, Third Edition book.
Original meal planA meat-free, plant-packed meal plan suitable for lacto-ovo vegetarians.
Vegetarian meal planThis tasty meal plan distributes protein evenly across each meal of the day to help curb cravings.
Higher Protein meal plan
This diet is not a fad. You’ve had enough of those and know the result. This is a program that helps you make simple, healthy, pleasurable changes that will result in a weight you can maintain for the rest of your life.
Donald D. Hensrud, MD, MS, MPH
All these features are available the moment you join:
The Mayo Clinic Diet program works by combining evidence-based nutrition guidance, personalized planning, and digital tools to support long-term, healthy weight loss. Here's how the program works:
In short, the Mayo Clinic Diet is more than a diet—it’s a comprehensive, medically backed weight loss program that gives you the tools, flexibility, and expert support to build healthier habits for life.
Where many diets stop |
Where Mayo Clinic Diet excels |
Weight loss only |
Whole-health focus – nutrition, habit change, movement, sleep and stress. |
Influencer-built |
Clinician-built – rooted in years of Mayo Clinic medical expertise. |
One-size-fits-all menus |
8 flexible meal plans with personalization via swap tools and the ability to "freestyle" to make the menus your own. |
Calorie math and extremes |
No calorie counting; unlimited fruit and vegetables with balanced portions. |
Little follow-up |
Unlimited group coaching and community so you’re not in this alone. |
No. The program teaches a food group “building-block” method – fill your plate with unlimited fruits and vegetables, then add lean protein, smart carbohydrates, and healthy fats. Portion visuals and the Diet Score keep you on track without spreadsheets.
The platform lets you choose (and freely switch between) eight delicious meal plans.
Highlights
Meal plan |
Ideal for |
Quick snapshot |
Busy schedules |
Ready-prepped ingredients, 15-minute meals, gluten-free option |
|
Low-carb lovers |
~50 g net carbs, heart-healthy fats such as olive oil and avocado |
|
Plant-forward eaters |
Lacto-ovo; protein via beans, soy, eggs, and dairy |
|
Heart health |
Emphasizes fish, nuts, legumes, extra-virgin olive oil |
|
Appetite control & muscle support |
Even protein distribution at each meal |
|
Cholesterol / blood-pressure concerns |
DASH-aligned, anti-inflammatory, cardio-protective foods |
|
Classic Mayo approach |
Based on the best-selling Mayo Clinic Diet book |
|
Members using weight-loss medications |
Higher protein, lower-volume portions |
Every meal plan includes a swap tool and grocery list, so accommodating dietary needs is as simple as one click.
Next step: Explore all meal plans or take a free Diet Score assessment .
Yes. The program is built to deliver safe, sustainable weight loss for adults of any gender.
Bottom line: Whether you’re male or female, the Mayo Clinic Diet’s evidence-based personalization, adaptable meal plans, and group coaching provide an effective path to lasting weight loss and better overall health.