Who qualifies for semaglutide injections?

There's a healthier way to lose weight with weight-loss medication. Discover the Mayo Clinic Diet for Weight-Loss Medications.

Semaglutide, a groundbreaking medication in the weight-management space, has emerged as a potential solution for individuals struggling with obesity. Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs mimic the effects of GLP-1, a naturally occurring hormone that regulates blood sugar levels and promotes a feeling of fullness.  

Semaglutide has shown remarkable efficacy in helping individuals lose weight and maintain a healthier lifestyle. Especially when combined with a healthy diet and regular exercise routine.

FDA-approved semaglutide injections

There are currently two FDA-approved semaglutide injections: 

• Ozempic is approved to lower blood sugar levels in adults with type 2 diabetes mellitus, in addition to diet and exercise. Ozempic is also approved to reduce the risk of heart attack, stroke, or death in adults with type 2 diabetes mellitus and known heart disease. 
• Wegovy is approved to help adults and children aged 12 years and older with obesity (BMI greater than 30 kg/m²) or some adults with overweight (BMI greater than 27 kg/m²), who also have weight-related medical problems, to lose weight and keep the weight off, in addition to diet and exercise. 

Both medications are only available with a prescription and may be covered by your health insurance.

Who should not take semaglutide

Semaglutide may not be suitable for everyone. Individuals with certain medical conditions or characteristics may not be eligible to take semaglutide. Some general contraindications and precautions associated with semaglutide include: 

1. Personal or family history of medullary thyroid carcinoma (MTC) 
2. If you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) 
3. Personal history of pancreatitis 
4. Pregnant and breastfeeding 
5. Gastrointestinal disease or gastroparesis 
6. Type 1 diabetes 
7. Patients under 12 years of age 

If you are curious to know if you qualify for semaglutide, the Mayo Clinic Diet for Weight-Loss Medications program offers a free eligibility quiz. The program is specifically designed for individuals taking weight-loss medications who are looking to adopt healthy new habits and maintain weight-loss for life.

Need a prescription for GLP-1s? The Mayo Clinic Diet platform now offers access to clinical care for members seeking a prescription to weight-loss medication such as GLP-1s. Check if you're eligible for weight-loss medication.