Lose weight with the Mayo Clinic Diet program

Designed by doctors at Mayo Clinic, this proven diet program supports your healthy weight journey, no matter where you start.

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What the Mayo Clinic Diet program includes

Discover Mayo Clinic’s science-backed diet plan, powered by the 100-point Diet Score that instantly shows how each choice fuels sustainable weight loss. Select from 8 balanced meal plans − Mediterranean, Healthy Keto, The Original, Heart Smart Superfoods, Protein Balance for GLP-1s, and more − or freestyle with our flexible food group system.

Your membership goes further with condition-specific guidance (heart health, diabetes, medication-assisted weight loss), unlimited group coaching, optional 1-on-1 sessions, and intuitive digital tools − trackers, grocery lists, home workouts, and a supportive community − to keep you on track from day one.

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8 delicious meal plans

8 delicious meal plans

The Mayo Clinic Diet uses a proprietary food groups system to help you create nutritionally balanced meals using real foods.

You have the choice of 8 different meal plans, including Simple, Healthy Keto, Mediterranean, Heart Smart Superfoods and Protein Balance for GLP-1s. 

Each meal is planned for you, but you can also make your own creations using the food groups system and our NEW Freestyle Guide.

Explore meal plans
8 delicious meal plans

Personalized weight loss programs

Personalized weight loss programs

Doctors recommend the Mayo Clinic Diet to improve health conditions such as cardiovascular disease and diabetes. 

If you are taking medication such as GLP-1s for weight loss or diabetes control, the Mayo Clinic Diet now has a weight-loss medication support program to help manage short- and long-term side effects, such as nausea and muscle loss.

Our programs
Personalized weight loss programs

Unlimited group coaching

Unlimited group coaching

Members have unlimited access to group coaching with experts such as Tara Schmidt, Lead Dietitian for the Mayo Clinic Diet.

The sessions cover how to use the program, nutrition, exercise and side effects from weight-loss medication.

We also offer 1-on-1 coaching with a Registered Dietitian to members with insurance coverage.

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Unlimited group coaching

Easy-to-use digital tools

Easy-to-use digital tools

The digital platform is packed with value and provides extensive support to help put the program into action. Members love these features:

  • Food tracker with barcode scanner
  • Comprehensive program guides
  • Meal plans and grocery lists
  • At-home exercise plans
  • Integration with your favorite fitness devices
  • Caring member community
  • The Mayo Clinic Diet ebooks
  • Plus, new Freestyle Guides for flexibility
What's new in 2025
Easy-to-use digital tools
5.3%
Average weight loss from the Mayo Clinic Diet digital program*
80%
More weight loss from the digital program vs an in-person experience*
13%
Average weight loss of responders to the Mayo Clinic Diet†
*Acosta, et al. (2024): Efficacy of in-person versus digital enhanced lifestyle interventions in adults with overweight and obesity, Obesity Pillars, Volume 12, 2024, 100133. https://doi.org/10.1016/j.obpill.2024.100133 † Mayo Clinic Diet - Weight Loss and Platform Usage: An analysis of Responders, Digital Wellness Report, August 2024

Compare the Mayo Clinic Diet meal plans for weight loss

Meal plan Core focus Best for
Simple Speed and convenience 15-minute dishes with ready-prepped ingredients; ideal for busy families and beginners.
Healthy Keto Low-carb, healthy fats About 50g net carbs featuring heart-smart fats (extra virgin olive oil, avocado, nuts); suits low-carb seekers.
Mediterranean Heart health focus Fish, legumes, nuts, and abundant produce; great for cardio wellness and plant-forward eaters.
Heart Smart Superfoods DASH and antioxidants Anti-inflammatory, cardio-protective foods; supports cholesterol and blood-pressure management.
Vegetarian Plant-based protein Lacto-ovo pattern with beans, soy, eggs, and dairy; fits meat-free members needing balanced macros.
Higher Protein Muscle support and satiety Evenly distributed protein to curb cravings; helps appetite control and strength goals.
Original (Book) Classic Mayo Clinic Diet plan DASH-style menus from the bestselling program; perfect for fans of the traditional Mayo Clinic Diet approach.
GLP-1 Support Medication companion Higher-protein, lower-volume portions; tailored to users on GLP-1 weight-loss medication.

The benefits go beyond weight loss

Membership from just $4/week

Your membership to the Mayo Clinic Diet is packed with value:

  • A bestselling diet from Mayo Clinic
  • Unlimited group coaching with Mayo Clinic experts
  • Personalized programs for healthy weight loss, heart health, diabetes and weight-loss medication support
  • 8 delicious meal plans including Mediterranean, Simple, Higher Protein and the New Heart Smart Superfoods
  • New daily Diet Score to boost success
  • New Freestyle Guides for flexibility
  • Easy-to-use tracking tools for weight, food, exercise and habits
  • 2 free Mayo Clinic eBooks
  • Access via our website or mobile apps
  • Access to a supportive, caring community

The Success Reward is not available in conjunction with promotional discounts or in-app purchases. If you would like to earn the Success Reward, purchase a standard-price subscription.