Weight loss for life

No tricks. No gimmicks. No nonsense.

If you’re ready to commit to making a real change in your life, we have a real solution — the New Mayo Clinic Diet offers a straightforward, affordable approach to effective, practical, and healthy weight loss.

Take our free 30-second Weight Loss Calculator to find out how much weight you could lose.

Free Weight Loss Calculator

"I lowered my health risks by losing 100 lbs* and my confidence has sky-rocketed!”

"I lowered my health risks by losing 100 lbs* and my confidence has sky-rocketed!”

We're excited to announce Mayo Clinic Diet has featured in 10 of 11 "Best Diets" categories in the U.S. News & World Report 2023. For the Mayo Clinic Diet, helping people lose weight and gain control of their health isn't simply a business — it's a key element of our larger mission as an international healthcare leader with unmatched medical expertise and innovation.

Featured in 10 of 11 “Best Diets” categories by U.S. News & World Report 2023

Best Diets Overall

Best Weight-Loss Diets

Easiest Diets to Follow

Best Diets for Healthy Eating

Best Diets for Diabetes

Best Heart Healthy Diets

Best Diets for Bone & Joint Health

Best Family-Friendly Diets

Best Plant-Based Diets

Best Diet Programs

Lose 3X more weight with a proven approach

Get easily accessible online resources that have helped hundreds of thousands of people lose weight.

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Lose 3X more weight with a proven approach

How much weight could you lose? Try our FREE Weight Loss Calculator.

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Complete the Free Weight Loss Calculator to discover:

  • How much weight you could lose on the Mayo Clinic Diet
  • A personalized plan for achieving your weight loss goals
  • Suggestions on how to improve your health by losing weight

You can meet your weight loss goals while enjoying great food. The Mayo Clinic Diet teaches a common sense, medically-sound approach to making smart decisions about eating — whether you’re dining in or out.

  • Forget counting calories and calculating points
  • Learn a common sense, medically-approved approach
  • Make smart decisions about eating

As seen on

US News
USA Today
Good Housekeeping

Hear from others like you

Donna’s personal journey to better health became professional. Since she started the New Mayo Clinic Diet, she’s 100 pounds lighter and enjoying a new career as a Certified Nutrition Coach.

Read her inspiring story

Hear from others like you

Nick realized he had to swap unhealthy habits for good ones. Today, he’s 50 pounds lighter and excited to see the improvements in his health.
Read his inspiring story…

Hear from others like you

Carol was diagnosed with pre-diabetes, pre-hypertension, and rising cholesterol. After a year on the New Mayo Clinic Diet, she’s down 47 pounds and feeling great.

Read her inspiring story

New in 2023: Unlimited Group Coaching

Members of the Mayo Clinic Diet have access to unlimited group coaching sessions with Mayo Clinic experts. These regular sessions help to support you, especially when you are starting the program.

Thom Rieck

Danielle Johnson

Angela Hazelton

Jennifer Welper

Meet our Trusted Health Professionals

This diet is not a fad. You’ve had enough of those and know the result. This is a program that helps you make simple, healthy, pleasurable changes that will result in a weight you can maintain for the rest of your life.

Donald D. Hensrud, MD, MS, MPH

Frequently asked questions

What’s included in the Mayo Clinic Diet?

  • A best-selling diet that is medically-backed and trusted worldwide
  • All-new digital platform that has helped members lose 3x more weight*
  • Access to the unparalleled educational content and expertise of the Mayo Clinic
  • Mayo Clinic Diet 12 Week Course to help you learn the principles of healthy weight loss
  • Exclusive content and videos from Mayo Clinic Doctors and Experts
  • All-new quick start Lose It! phase, where members can lose 6 to 10 lbs in 2 weeks
  • Tools to track progress and log your meals, exercise, measurements, and body weight
  • All-new quick, easy, healthy, and delicious recipes
  • All-new Habit Optimizer to swap unhealthy habits for good ones
  • Meal plan options that include Healthy Keto, High Protein, Vegetarian and Mediterranean
  • Holistic and whole self-focused program
  • Calorie counting not required
  • Food tracker with over 1m foods
  • Enjoy unlimited fruits and vegetables
  • At-home workouts – no equipment required
  • Psychological quiz to assess diet mindset
  • Unlimited access to a members' Private Facebook Group

How long is the program?

Our initial program is 12 weeks but Mayo Clinic Diet is built for your life. Health is a journey and we’re here every step of the way, for as long as you need us.

What makes the Mayo Clinic Diet different from other online weight loss programs?

With many programs, losing weight is the only point. The New Mayo Clinic Diet is designed to inspire hope and promote lasting, life-long health. Built on the unparalleled expertise of the Mayo Clinic, the New Mayo Clinic Diet only weight loss program that features a comprehensive, whole-health menu that is supported by the worldwide leader in healthcare.

How does the program work?

Please visit the How It Works page to learn more about the New Mayo Clinic Diet program. 

Do I have to count calories?

No, the New Mayo Clinic Diet is about making sure you’re getting enough of the foods that are right for you. We are not focused on calorie counting.

What if I’m vegan, vegetarian or keto?

The New Mayo Clinic Diet has extensive menus for both vegetarian and healthy keto.