The Mayo Clinic Diet is a lifelong, sustainable approach to weight loss
We focus on whole-food nutrition, making healthy eating straightforward with no need for calorie counting.
We delve into the science of behavior, helping you understand and improve your eating habits for lasting change.
The Mayo Clinic Diet is built on decades of medical research and evidence-based strategies for healthy weight loss.
Gain access to a network of experts dedicated to supporting your weight loss journey with strategies that go beyond the scale.
A personalized weight loss plan is a tailored approach to weight management that adapts to your individual lifestyle, preferences, and any health conditions you may have. Instead of a one-size-fits-all solution, it provides flexible options that let you choose what works best for your goals and daily routine. At the Mayo Clinic Diet, we use your unique health profile to match you with the right tools, meal plans, and expert guidance—so your path to weight loss is truly your own.
The Mayo Clinic Diet starts by getting to know you—your health goals, past weight loss experiences, dietary preferences, and any medical conditions you may be managing. Based on your profile, we recommend one of our 8 expert-designed meal plans for weight loss. You’re free to switch plans or customize meals anytime, giving you the flexibility to enjoy food you love while making meaningful progress on your health journey.
In 2025, the Mayo Clinic Diet offers four comprehensive online weight loss programs:
As a member, you get full access to all four programs and the digital tools that support them—no extra fees or upgrades required.
With the Mayo Clinic Diet, you can choose from 8 delicious, science-backed meal plans for weight loss:
Three of our most popular plans—Simple, Original, and Mediterranean—are also available in gluten-free versions. Every plan is designed by dietitians to ensure you’re eating well while losing weight safely and sustainably.
Most members can expect to lose 6–10 pounds in the first two weeks, and about 5% of their body weight within 3 months. Those who embrace the program lose 13% of their body weight within 6 months. Your results may vary, but with a personalized plan and the right support, meaningful weight loss is absolutely within reach.
Yes! The Mayo Clinic Diet includes a dedicated 24-week program designed specifically for people using weight-loss medications like GLP-1s. It features a special ebook, The Mayo Clinic Diet for Weight-Loss Medications, along with the exclusive Protein Balance for GLP-1s meal plan. This plan helps you get the nutrition you need to support your medication and your weight loss goals.
Your membership includes a suite of smart digital tools to help you stay on track, including:
These tools are designed to make healthy habits easier and more rewarding every day.
It’s easy! Simply become a member by signing up—plans start at just 55 cents per day. Not ready to commit? Try our free Personalized Plan experience to explore your best-fit weight loss options and get a sneak peek at the tools and meal plans that make the Mayo Clinic Diet one of the most trusted weight loss programs online.