Our commitment to your health
The Mayo Clinic Diet emphasizes healthy eating and sustainable behavior modifications. We avoid fad diets and quick fixes, focusing instead on evidence-based strategies designed for long-term success.
The free assessment covers your:
- Diet history and preferences
What's your experience with diet plans? Do you have a preferred eating style? - Lifestyle factors
What matters most to you in a program? What's getting in the way of your weight loss? - Weight loss objectives
What's your starting point? How much weight do you intend to lose? - Health history
Do you have any pre-existing health conditions? Are weight-loss medications an option?
Take the first step
Complete the Mayo Clinic Diet assessment today. This is an essential step towards achieving your weight loss objectives. Whether you're looking for a healthy weight-loss plan or considering weight-loss medication, discover which of our world-leading solutions is best for you. Together, let's make healthy happen!
What members say about the Mayo Clinic Diet
So easy to follow
The Mayo Clinic Diet is so easy to follow. I love the different plans you can choose from and swap between. All the recipes are amazing and easy to make. If you don't like an ingredient or recipe, you can swap for something else. I like how there is a gluten free meal plan. This is definitely one diet I will stick to.
Great education and guidance
The diet, exercise, and behaviors presented through the program helped me reach and maintain my weight loss goal. I could get close on my own but could not break through the final 10 pounds. A key enabler was being able to [freestyle] meal planning while following calorie and nutrition guidance.
The perfect plan
For me, Mayo Clinic Diet is perfect. The two-week start takes the guess work out of what to eat. You get grocery lists and simple, satisfying recipes. The encouragement to address habits that inhibit or propel weight loss is also a wonderful feature. The program truly addresses everything you need to succeed.
What Mayo Clinic Diet stands for
The Mayo Clinic Diet is a lifelong, sustainable approach to weight loss
Practical nutrition
We focus on whole-food nutrition, making healthy eating straightforward with no need for calorie counting.
Understanding habits
We delve into the science of behavior, helping you understand and improve your eating habits for lasting change.
Science-backed guidance
The Mayo Clinic Diet is built on decades of medical research and evidence-based strategies for healthy weight loss.
Expert-driven support
Gain access to a network of experts dedicated to supporting your weight loss journey with strategies that go beyond the scale.
Frequently asked questions
What is a personalized weight loss plan?
A personalized weight loss plan is a tailored approach to weight management that adapts to your individual lifestyle, preferences, and any health conditions you may have. Instead of a one-size-fits-all solution, it provides flexible options that let you choose what works best for your goals and daily routine. At the Mayo Clinic Diet, we use your unique health profile to match you with the right tools, meal plans, and expert guidance—so your path to weight loss is truly your own.
How does the Mayo Clinic Diet create a personalized meal plan for weight loss?
The Mayo Clinic Diet starts by getting to know you—your health goals, past weight loss experiences, dietary preferences, and any medical conditions you may be managing. Based on your profile, we recommend one of our 8 expert-designed meal plans for weight loss. You’re free to switch plans or customize meals anytime, giving you the flexibility to enjoy food you love while making meaningful progress on your health journey.
Which diet programs online are available in 2025?
In 2025, the Mayo Clinic Diet offers four comprehensive online weight loss programs:
- Mayo Clinic Diet—our classic program based on the New York Times best-selling book
- Heart Health program—designed for those managing high blood pressure, cholesterol, or heart disease
- Diabetes program—tailored for people with prediabetes or type 2 diabetes
- Weight-Loss Medications program—for those using GLP-1s and similar medications
As a member, you get full access to all four programs and the digital tools that support them—no extra fees or upgrades required.
What meal plans for weight loss can I choose inside the program?
With the Mayo Clinic Diet, you can choose from 8 delicious, science-backed meal plans for weight loss:
- Simple
- Original
- Higher Protein
- Mediterranean
- Healthy Keto
- Vegetarian
- Heart Smart Superfoods
- Protein Balance for GLP-1s
Three of our most popular plans—Simple, Original, and Mediterranean—are also available in gluten-free versions. Every plan is designed by dietitians to ensure you’re eating well while losing weight safely and sustainably.
How much weight can I expect to lose with a personalized plan?
Most members can expect to lose 6–10 pounds in the first two weeks, and about 5% of their body weight within 3 months. Those who embrace the program lose 13% of their body weight within 6 months. Your results may vary, but with a personalized plan and the right support, meaningful weight loss is absolutely within reach.
Does the program support people using weight-loss medications?
Yes! The Mayo Clinic Diet includes a dedicated 24-week program designed specifically for people using weight-loss medications like GLP-1s. It features a special ebook, The Mayo Clinic Diet for Weight-Loss Medications, along with the exclusive Protein Balance for GLP-1s meal plan. This plan helps you get the nutrition you need to support your medication and your weight loss goals.
What digital tools and coaching are included?
Your membership includes a suite of smart digital tools to help you stay on track, including:
- Daily food, exercise, and habit trackers
- The Diet Score tool, offering real-time feedback on your progress
- Group coaching led by Mayo Clinic experts
- Optional one-on-one sessions with registered dietitians
These tools are designed to make healthy habits easier and more rewarding every day.
How do I get started with my personalized weight loss plan?
It’s easy! Simply become a member by signing up—plans start at just 55 cents per day. Not ready to commit? Try our free Personalized Plan experience to explore your best-fit weight loss options and get a sneak peek at the tools and meal plans that make the Mayo Clinic Diet one of the most trusted weight loss programs online.