Personalized weight loss programs

As a member of the Mayo Clinic Diet, you're supported at every step with personalized programs for weight loss, heart disease, diabetes, and weight-loss medication.

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The Mayo Clinic Diet

The Mayo Clinic Diet

The original healthy weight loss program based on the bestselling book, The Mayo Clinic Diet, Third Edition.

  • 12 week program with exclusive content from Mayo Clinic
  • Explores nutrition, healthy eating, exercise, and well-being
  • Includes 7 meal plans including the much-loved Simple plan
  • Includes 2 free Mayo Clinic ebooks
  • Available with any membership to the Mayo Clinic Diet  
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The Mayo Clinic Diet

The Mayo Clinic Diet for Heart Health

The Mayo Clinic Diet for Heart Health

  • 24 week program for members with hypertension, high cholesterol or heart disease
  • Discover how to improve or even reverse heart conditions
  • Naturally reduce blood pressure by 5-13 mm Hg
  • Choice of 7 meal plans including Mediterranean
  • Covers healthy diet, exercise, quality sleep and stress management
  • Available with any membership to the Mayo Clinic Diet  
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The Mayo Clinic Diet for Heart Health

The Mayo Clinic Diet for Weight-Loss Medications

The Mayo Clinic Diet for Weight-Loss Medications

  • 24 week program for members using weight-loss medications such as GLP-1s
  • Learn how to manage side effects and prevent rebounds
  • Choice of 7 meal plans including Protein Balance for GLP-1s
  • Includes the exclusive ebook, The Mayo Clinic Diet, Weight-Loss Medications Edition
  • Available with any membership to the Mayo Clinic Diet  
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The Mayo Clinic Diet for Weight-Loss Medications

The Mayo Clinic Diet for Diabetes

The Mayo Clinic Diet for Diabetes

  • 12 week program for members with prediabetes or diabetes
  • Improve your A1c through healthy eating and exercise
  • Choice of 7 meal plans, all with carb counts to support blood glucose control
  • Covers healthy eating, exercise, well-being and the complications of diabetes
  • Includes the ebook, The Mayo Clinic Diet for Diabetes
  • Available with any membership to the Mayo Clinic Diet  
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The Mayo Clinic Diet for Diabetes

Designed at Mayo Clinic. Tailored by you.

NEW IN 2026

The most personal Mayo Clinic Diet ever

Your journey with the Mayo Clinic Diet starts with a plan that fits you—your health, preferences, and lifestyle. The program is designed to make healthy eating simple, enjoyable, and sustainable, no matter your starting point.

  • Built for your health needs
  • Matches your eating style
  • Respects your allergies and intolerances
  • Reflects your food likes and dislikes
  • Fits your schedule
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80% more weight loss

Research shows that members of the Mayo Clinic Diet lose 80% more weight than participants of an in-person program. The comprehensive support of the digital program helps deliver these clinically-significant results.

Acosta, et al. (2024): Efficacy of in-person versus digital enhanced lifestyle interventions in adults with overweight and obesity, Obesity Pillars, Volume 12, 2024, 100133. https://doi.org/10.1016/j.obpill.2024.100133

The benefits go beyond weight loss