The original healthy weight loss program based on the bestselling book, The Mayo Clinic Diet, Third Edition.
NEW IN 2026
Your journey with the Mayo Clinic Diet starts with a plan that fits you—your health, preferences, and lifestyle. The program is designed to make healthy eating simple, enjoyable, and sustainable, no matter your starting point.
Research shows that members of the Mayo Clinic Diet lose 80% more weight than participants of an in-person program. The comprehensive support of the digital program helps deliver these clinically-significant results.
Acosta, et al. (2024): Efficacy of in-person versus digital enhanced lifestyle interventions in adults with overweight and obesity, Obesity Pillars, Volume 12, 2024, 100133. https://doi.org/10.1016/j.obpill.2024.100133