Your companion to weight-loss medication from the experts at Mayo Clinic

Our program helps you achieve life-changing weight loss while managing the side effects of medications such as GLP-1s.

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Healthy weight loss with medication, the way the FDA approved it

The Mayo Clinic Diet for Weight-Loss Medications offers the structure and support you need to achieve healthy, successful weight loss with medication such as GLP-1s. Membership includes these top-rated features.

Protein Balance meal plan

This higher protein meal plan helps prevent muscle loss associated with GLP-1s. It's just one of the 7 delicious meal plans you'll have access to. 

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Personalized journey

We'll map out your year ahead on weight-loss medication to help you develop skills for sustainable weight loss. Your journey continues even when medication stops.

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Group coaching with Mayo Clinic experts

This is your opportunity to learn from experts and ask questions in real-time. Topics include nutrition, exercise and managing the side effects of weight-loss medication. 

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Weight-loss medications ebook

Membership includes 2 complimentary ebooks: The Mayo Clinic Diet: Weight-Loss Medications Edition and Cook Smart, Eat Well. Enjoy them on your computer, tablet or mobile phone.

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24 weeks of education

Our program covers everything you need to know about losing weight with weight-loss medication and maintaining your goals once you've stopped medication.

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At-home exercise plans

Our resistance exercise plan can help prevent muscle loss, a side effect of weight-loss medication. All workouts can be done at home with no equipment.  

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Easy-to-use tracking tools

Develop the skills for lifelong weight management with 5-star rated food, weight and habit tracking tools that keep you accountable. 

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Community support

Our Private Facebook Group has been described as one of the happiest places on social media. Here, members share the ups, downs and non-scale victories that make the program so popular.

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Did you know?

The Food & Drug Administration approved GLP-1s for weight loss as part of a weight management program. They were not designed to be used alone.

Help to manage side effects

Our program is packed with tools and advice to help you manage the side effects of weight-loss medication. Here, Tara Schmidt, Lead Dietitian for the Mayo Clinic Diet, explains how to manage low appetite.

Average weight loss with a program like Mayo Clinic Diet and weight-loss medication*
More weight loss from the Mayo Clinic Diet digital program than an in-person experience†
Savings account eligible
*Based on a 68-week clinical trial, patients without diabetes but with a BMI of ≥30, or ≥27 lost an average of 15% of their body weight (-33.6 lbs) on 2.4 mg semaglutide, when combined with a reduced-calorie diet and increased physical activity. Wegovy® is FDA-approved for weight management. †Acosta, et al. (2024): Efficacy of In-Person and Digital Lifestyle Interventions in Patients with Overweight and Obesity.

We're invested in your success

Our Companion subscription provides access to the Mayo Clinic Diet for Weight-Loss Medications and starts at $49.99 per month. You can save up to 67% by paying upfront. Members who pay upfront on select plans are also eligible for a Success Reward of up to $75.

The companion subscription includes:

  • A best-selling diet from Mayo Clinic
  • Choice of 7 delicious meal plans
  • Unlimited group coaching with Mayo Clinic experts
  • 2 free eBooks
  • Easy-to-use tracking tools for weight, food, exercise and habits
  • Access via our website or mobile apps
  • Access to a supportive, caring community
  • A Success Reward of up to $75* 

*Conditions apply. See the Success Reward criteria.