5 ways to increase weight loss on Wegovy

There's a healthier way to lose weight with weight-loss medication. Discover the Mayo Clinic Diet for Weight-Loss Medications.

Wegovy, also known as semaglutide, is a prescription drug that has been approved by the FDA for weight loss in adults with obesity or overweight with at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol). Experts have proven Wegovy's effectiveness for weight loss, but it is not a magic bullet. For best weight-loss results and good health, it’s important to take Wegovy along with making lifestyle changes.  

If you are trying to lose weight and taking, or considering taking, Wegovy, here are 5 ways to boost your chances of success. 

1. Eat a healthy diet

Wegovy helps to reduce appetite and calorie intake. For best results, you should take Wegovy while following a low-calorie diet. Aim for at least 1,200 calories per day and choose foods that are nutrient dense and easy to consume.  

Focus on foods like fruits, vegetables, lean proteins, and whole grains. Include a protein-rich ingredient at each main meal, choosing from fish, beans, tofu, eggs, poultry, lean meat, or reduced-fat dairy. You may experience a poor appetite and struggle to eat because of the initial common side effects of the medication. Try making high-protein smoothies or blended vegetable and bean soups to ensure you’re getting enough essential nutrients.  

By following a healthy, nutritious eating plan, you can harness the full potential of Wegovy and improved health. 

2. Embrace a physically active lifestyle

Exercise is foundational in any weight-loss program, but particularly important while taking weight-loss medications for two key reasons.  

Firstly, engaging in aerobic exercises such as brisk walking, jogging, or cycling can expedite calorie burning and improve cardiovascular health.  

Secondly, strength training helps maintain and build muscle, which boosts metabolism and improves weight loss success in the long run.  

Because loss of muscle occurs with any type of weight-loss intervention, this type of exercise is crucial. Adding physical activity to your daily routine, can maximize the benefits of Wegovy. It can also help you keep the weight off long-term.

3. Prioritize sleep and stress management

Sleep and stress also play significant roles in weight management. Inadequate or poor-quality sleep can disrupt the body’s ability to regulate appetite.  

This disruption can lead to increased hunger, making it more challenging to maintain a calorie-controlled diet. Additionally, lack of sleep can result in fatigue and decreased motivation for physical activity, further hindering weight management efforts. Stress can also contribute to weight gain. 

When stressed, you may turn to comfort foods that are high in sugar or fat as a coping mechanism. Moreover, stress triggers the release of cortisol, a hormone that can promote the accumulation of abdominal fat.

The combination of poor sleep and high stress levels can make it more difficult to achieve and maintain a healthy weight. If you struggle to get a good night’s sleep, try these tips: 

  • Define and stick to a sleep schedule
  • Create a restful environment
  • Perform calming activities before bed  

If your stress is out of control, try refocusing your mind by adopting stress management techniques such as meditation, yoga, or seeking out professional support. 

4. Tailor your dose of Wegovy

Like with other medications, individual responses to weight-loss medications vary. When starting Wegovy, you are likely to start on a lower dose and gradually increase the dose up to a maximum of 2.4 mg weekly.  

It’s best to work with your healthcare provider to ensure that you are receiving the most effective dosage of Wegovy suitable for you. This may not necessarily mean the highest possible dose, but one that works for you without frequent or bothersome side effects.  

By tailoring your treatment plan, you can maximize the benefits of Wegovy and achieve sustainable weight-loss results. 

5. Commit to long-term lifestyle changes

While Wegovy jumpstarts weight loss, it is normal to experience weight-loss plateaus or even gains at some point. Staying consistent and committed to a healthy lifestyle is important. This way you can maintain your weight-loss achievements and safeguard against weight regain.  

Embrace a nutrient-dense diet, stay physically active, prioritize sleep, manage stress, and build a strong support crew. Using tracking tools for food intake, weight, and habits can help you stay on track and motivated. Remember that the scale is not your only proof of success. List your off-scale victories too, like improvements in your health, confidence, or stamina.  

Medications like Wegovy work best when used with a healthy lifestyle program, such as the Mayo Clinic Diet.

The Mayo Clinic Diet can support you

Our new Mayo Clinic Diet for Weight-Loss Medication program can help support your medical weight loss while taking Wegovy. The program offers a meal plan designed specifically for those taking weight-loss medication. 

It also includes an exercise plan to maximize fat loss and minimize muscle loss. Members receive support from both peers and experts. Additionally, members have access to tools that track progress using scientific methods. 

Need a prescription for GLP-1s? The Mayo Clinic Diet platform now offers access to clinical care for members seeking a prescription to weight-loss medication such as GLP-1s. Check if you're eligible for weight-loss medication.

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