If you’re looking for a delicious way to improve your health and lose weight, the Mediterranean meal plan might just be your perfect match. Rooted in the traditional eating habits of countries bordering the Mediterranean Sea, this lifestyle emphasizes fresh, whole foods and a balanced, sustainable approach to eating. It’s praised not just for its flavor, but for its well-documented benefits on heart health, weight management, and overall well-being.
At the Mayo Clinic Diet, you can go beyond the basics with a structured 6-week Mediterranean meal plan designed to help you build healthy habits, lose weight and reach your wellness goals.
Whether you’re a busy professional or managing meals for a family, these flexible, professionally developed plans make it easy to enjoy nourishing, satisfying meals every day.
The Mediterranean meal plan is inspired by the traditional cuisines of Greece, Italy, and other coastal cultures that celebrate seasonal produce, whole grains, and heart-healthy fats. It’s not a strict diet, but a lifestyle built on mindful eating, social meals, and sustainable choices.
Core principles include:
At the Mayo Clinic Diet, this classic approach is tailored for modern life with meal plans that are easy to follow, dietitian-approved, and fully portion-controlled for weight loss. As a member, your meal plan will include flavorful, heart-healthy eating with breakfast, lunch, dinner and snacks suggestions all while having the freedom to swap meals and generate customized grocery lists.
Whether you’re following the traditional 6-week plan or exploring the new and improved Heart Smart Superfoods meal plan, you’ll have a structured path that fits your preferences and supports long-term health.
Backed by decades of research, the Mediterranean diet is widely regarded as one of the healthiest eating patterns in the world. Among its most studied benefits:
The Heart Smart Superfoods plan—available exclusively through the Mayo Clinic Diet—takes these benefits even further. By integrating lesser-known, cardio-protective foods such as cocoa and chili, it optimizes heart health outcomes beyond the traditional plan.
This evidence-based approach gives members not only access to healthy Mediterranean recipes, but the tools to make impactful, science-backed changes in a way that’s simple and sustainable.
Foods to enjoy often
Foods to limit
The Mayo Clinic Diet’s Mediterranean meal plan is built with portion guidance baked in. Whether you’re prepping a breakfast parfait or enjoying a hearty lentil soup, you’ll know exactly how much to eat for optimal nutrition and weight loss. This structure supports a balanced diet plan while reducing the guesswork of healthy eating.
And if something doesn’t suit your taste, no problem—you can swap meals, customize your week, and still stay on track with your health goals.
Here’s a delicious example of what a day on the Mayo Clinic Diet’s Mediterranean meal plan might look like. Every meal is perfectly portioned to support optimal nutrition and weight loss, with flexibility to suit your tastes and lifestyle:
These meals reflect the simplicity and flavor of the Mediterranean diet recipes curated by Mayo Clinic Diet experts. Whether you’re new to the Mediterranean lifestyle or looking to refine your routine, you’ll find variety, balance, and convenience in each day’s plan.
As a member, you can swap out meals you don’t love, generate a personalized grocery list, and follow a step-by-step guide for weekly Mediterranean meal prep—making it easy to stay on track and enjoy every bite.
Success starts at the store. Here’s how to keep your kitchen stocked for success:
The Mayo Clinic Diet makes this even easier. Each Mediterranean meal plan includes a pre-built shopping list based on your weekly menu—saving you time and making meal prep a breeze. Plus, you’ll always know you’re getting exactly what you need for your heart-healthy eating goals.
A Mediterranean lifestyle is about more than food. It’s a mindset:
These principles are woven throughout the Mayo Clinic Diet platform, which supports your full wellness journey—not just your diet. You’ll get encouragement, tracking tools, and insights to reinforce lasting change.
The Mediterranean meal plan is more than a diet—it’s a sustainable path to better health. And the Mayo Clinic Diet helps you make the most of it.
Whether you’re starting with the 6-week Mediterranean meal plan or leveling up with the 12-week Heart Smart Superfoods menu, you’ll enjoy flexible, expertly designed meals that support both weight loss and heart health. Each meal is portioned for success, packed with flavor, and easy to prepare. Sign up for the Mayo Clinic Diet and get started today.
In this video, Dr. Francisco Lopez-Jimenez, a Mayo Clinic cardiologist, explains the essentials of a heart-healthy diet.
The Mediterranean meal plan isn’t just a flavorful way to eat—it’s a powerful strategy within the Mayo Clinic Diet to help you reach and sustain your weight loss and heart health goals. Whether you’re aiming to slim down, reduce your risk for cardiovascular disease, or both, this plan offers structure, science, and flexibility grounded in the Mayo Clinic’s clinical expertise.
When paired with the Mayo Clinic Diet for Heart Health program, the Mediterranean approach can help naturally lower blood pressure and cholesterol thanks to its focus on nutrient-dense foods, healthy fats, and low-sodium ingredients.
And the results speak for themselves. According to a 2024 study published in Obesity Pillars, members following the Mayo Clinic Diet lose, on average, 5.3% of their body weight within six months. Even more impressively, “responders”—the top 20% of members—lose an average of 13.1% of their body weight over the same period. These are life-changing outcomes, achieved through sustainable, supportive behavior change—not crash dieting.
As a member, you’ll have access to a suite of tools and resources that make success simpler:
With structure, evidence-based tools, and ongoing support, the Mediterranean meal plan through the Mayo Clinic Diet empowers you to eat well, feel better, and achieve meaningful health results.
This variation combines the Mediterranean diet with intermittent fasting: eat normally five days a week and reduce calorie intake on two non-consecutive days. It’s a popular option for weight management, but not essential for success on the Mayo Clinic Diet.
A day might include Greek yogurt with berries for breakfast, a lentil salad with olive oil dressing for lunch, grilled fish with vegetables for dinner, and a small serving of almonds as a snack.
Water, herbal teas, and coffee are the best choices. To support weight loss and overall health, it’s best to avoid sugary beverages and limit or skip alcohol. The Mayo Clinic Diet recommends building hydration habits that align with your goals.
There’s no single “best,” but favorites include citrus fruits, berries, apples, figs, and grapes—each rich in fiber and antioxidants that support heart and metabolic health.
References
Mayo Clinic. Mediterranean diet: A heart-healthy eating plan
Estruch R, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. New England Journal of Medicine, 2013.
Mayo Clinic. Heart-healthy diet: 8 steps to prevent heart disease
Acosta, et al. (2024): Efficacy of in-person versus digital enhanced lifestyle interventions in adults with overweight and obesity, Obesity Pillars, Volume 12, 2024, 100133. https://doi.org/10.1016/j.obpill.2024.100133.
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